For a single episode of deep vein thrombosis (DVT), what is the recommended duration for apixaban treatment?

The recommended duration for apixaban treatment for a single episode of deep vein thrombosis (DVT) is typically 3 to 6 months. In most clinical guidelines, the standard recommendation is 3 months of anticoagulation therapy for an initial DVT, and extending to 6 months may be appropriate based on the patient's risk factors for recurrence or bleeding. Therefore, for a single episode of DVT treated with apixaban, 3 months is generally adequate, and the treatment can be extended to 6 months if there are specific indications, such as high risk for recurrence. This approach balances the need for effective anticoagulation while minimizing the risks of prolonged anticoagulation therapy, such as bleeding complications. The choice of 6 months reflects consideration of additional factors that might lead a clinician to opt for extended treatment.