In terms of INR, what is the typical therapeutic range for patients receiving warfarin?

The typical therapeutic range for patients receiving warfarin is 2.0 - 3.0. This range is established for most indications, including the prevention of thromboembolism in patients with atrial fibrillation or mechanical heart valves.

Warfarin functions as an anticoagulant by inhibiting vitamin K-dependent clotting factors. Maintaining the INR (International Normalized Ratio) within the therapeutic range is crucial for ensuring that a patient receives adequate anticoagulation to prevent blood clots while minimizing the risk of bleeding complications. An INR below 2.0 may not provide sufficient anticoagulation, whereas an INR above 3.0 increases the risk of serious bleeding.

While adjustments may be necessary based on individual patient factors such as specific conditions or responses to treatment, the range of 2.0 - 3.0 is standard for most patients on warfarin therapy. Higher therapeutic ranges, such as 2.5 - 3.5 or 3.0 - 4.0, may be appropriate for specific high-risk situations, but they are not considered the typical target for the general population receiving warfarin.