What are the two main types of calcium channel blockers?

Calcium channel blockers (CCBs) are categorized primarily into two categories: dihydropyridines and non-dihydropyridines. Dihydropyridine CCBs primarily target peripheral vascular smooth muscle, leading to vasodilation and are commonly used to treat hypertension and angina. Examples include amlodipine and nifedipine.

On the other hand, non-dihydropyridine CCBs affect both the vascular smooth muscle and the conduction system of the heart, making them effective for conditions involving heart rhythm irregularities and supraventricular tachycardia. Examples include verapamil and diltiazem.

Understanding the distinctions between these two types of CCBs is important for their appropriate clinical application, as they have different mechanisms of action and therapeutic uses. This classification aids pharmacists and healthcare providers in making informed decisions regarding treatment regimens for patients.