What is a common side effect of SSRIs during the initial treatment phase?

During the initial treatment phase of selective serotonin reuptake inhibitors (SSRIs), a common side effect is a temporary increase in anxiety and depression. This phenomenon can occur because SSRIs impact serotonin levels in the brain, but it may take time for the full therapeutic effects to manifest. As the body adjusts to the medication, there can be an exacerbation of symptoms before improvement is noted, which might be distressing for patients.

In contrast, increased energy levels might be expected as a result of improved mood over time but is not a typical immediate effect. Significant weight loss is generally not associated with SSRIs; rather, some patients may experience weight gain with prolonged use. Improved sleep quality is another potential benefit of SSRIs, but similar to increased energy, it often occurs after the initial adjustment period rather than as a common early side effect. Thus, the temporary increase in anxiety and depression stands out as a notable and well-documented reaction during the early stages of SSRI treatment.