What is a common symptom of megaloblastic anemia?

Megaloblastic anemia is characterized by the presence of large, immature, and dysfunctional red blood cells in the bloodstream, primarily due to a deficiency of vitamin B12 or folate. One of the hallmark symptoms of this condition is fatigue and weakness. This occurs because the impaired red blood cell production leads to insufficient oxygen delivery to the body's tissues, which manifests as a general feeling of tiredness and lack of energy. The body struggles to carry out normal metabolic processes efficiently, resulting in noticeable fatigue.

Other symptoms of megaloblastic anemia may include pallor, shortness of breath, and in some cases, neurological symptoms if vitamin B12 deficiency is present. Increased energy levels, improved cognitive function, and normal appetite are not associated with megaloblastic anemia and would not represent the physiological reality of an individual suffering from this condition.