What is the recommended duration of apixaban treatment for multiple episodes of DVT?

The recommended duration of apixaban treatment for multiple episodes of deep vein thrombosis (DVT) is that it may be considered lifelong in certain patients. This is particularly the case for individuals who have had multiple unprovoked DVT events, as the risk of recurrent thrombosis is significantly elevated in these situations. Long-term anticoagulation therapy helps prevent new clots from forming and reduces the risk of post-thrombotic syndrome, which can significantly affect a patient’s quality of life.

While 6 months or 1 year are acceptable treatment durations for initial or provoked DVT cases, lifelong therapy becomes a consideration for those with recurrent DVT or in cases where continuing risk factors are present. This approach is often tailored to the individual patient's risk factors, history, and treatment response, hence the recommendation for a more permanent anticoagulation strategy in certain contexts.