What should be monitored when using azathioprine?

When using azathioprine, it's essential to monitor the complete blood count (CBC) due to the medication's potential effects on bone marrow suppression. Azathioprine is an immunosuppressive drug primarily used in the treatment of autoimmune conditions and to prevent transplant rejection. One of its significant side effects is myelosuppression, which can lead to decreased levels of red blood cells, white blood cells, and platelets. Monitoring the CBC allows healthcare providers to detect any hematologic abnormalities early, ensuring timely intervention if necessary.

While there are other parameters that may be monitored during treatment with azathioprine, such as liver function tests and even electrolytes in some cases, the complete blood count is the most critical to watch for as it directly relates to the safety and efficacy of the therapy.